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Tazemetostat
  • Synonyms: EPZ-6438
  • ATC: L01X
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:572.75 g/mol
  • CAS-RN:1403254-99-8
  • InChI Key:NSQSAUGJQHDYNO-UHFFFAOYSA-N
  • InChI:InChI=1S/C34H44N4O4/c1-​5-​38(29-​10-​14-​41-​15-​11-​29)​32-​20-​28(27-​8-​6-​26(7-​9-​27)​22-​37-​12-​16-​42-​17-​13-​37)​19-​30(25(32)​4)​33(39)​35-​21-​31-​23(2)​18-​24(3)​36-​34(31)​40/h6-​9,​18-​20,​29H,​5,​10-​17,​21-​22H2,​1-​4H3,​(H,​35,​39)​(H,​36,​40)

Substance Classes

Synthesis Path

Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
1975-50-4 C8H7NO4 2-methyl-3-nitrobenzoic acid
77-48-5 C5H6N2O2 1,3-dibromo-5,5-dimethyl-2,4-imidazolidinedione
220514-28-3 C9H8BrNO4 methyl 3-amino-5-bromo-2-methyl benzoate
29943-42-8 C5H8O2 dihydro-2H-pyran-4(3)one
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsit

References

    • Knutson, S. K. et al., Proc. Natl. Acad. Sci USA, (2013) 110(19), 7922-7927.
    • WO 9999 999999 (Epizyme/Eisai Co; 18.10.2012; appl. 13.4.2012; USA-prior. 13.4.2011).
    • WO 9999 999999 (Epizyme/Eisai Co; 17.10.2013; appl. 11.4.2013).
    • WO 9999 999999 (Epizyme/Eisai Co; 23.4.2015; appl. 15.10.2014; USA-prior. 16.10.2013).

  • EZH2 inhibitors for treating lymphona:

    • WO 9999 999999 (Epizyme; 23.12.2015; appl. 17.6.2015; USA-prior. 17.6.2014).
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